Ginkgo biloba is the world\'s oldest living species of tree. Individual trees live as long as 1,000 years. Ginkgo grows most predominantly in the southern and eastern U.S, southern France, China, and Korea. It is the leaves of the tree that is used in herbal medicine.Historical or traditional useMedical use of gingko can be traced back almost 5,000 years in Chinese herbal medicine. The nuts of the tree were most commonly recommended and used.Active constituentsThe medical benefits of Ginkgo extract are attributed primarily to two groups of active constituents: the ginkgo flavone glycosides and terpene lactones. Ginkgo flavone glycosides are primarily responsible for ginkgo\'s anti-oxidant activity. These two actions may help ginkgo to maintain normal circulatory function, and support the brain and central nervous system. - 90 (size L)